Search: "human"

Launch Loki Mode autonomous SDLC agent. Handles PRD-to-deployment with minimal human intervention. Invoke for multi-phase development tasks, bug fixing campaigns, or full product builds.

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), scores variants or scans windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and builds Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.

Use when executing an implementation plan in the current session as the implementer yourself — your human partner chose inline execution, or no subagent tool is available

Supports multivariate severity assessment and exploratory endpoint-time score forecasting for laboratory animal studies using the RELSA (RELative Severity Assessment) score and ARIMA-based foRcast forecasting. Use when combining welfare readouts — body weight or weight loss, body temperature, clinical or nesting scores, biomarkers, activity, heart rate, burrowing, wheel running — into one severity score per animal per day, when asking which animals are at risk of reaching a humane endpoint at a specified future observation time, when defining attention/danger zones or thresholds on a severity scale by kernel density estimation, or when reporting severity for a 3Rs, refinement, animal-welfare, or EU Directive 2010/63/EU severity-assessment context. Covers directionality ("turned" variables), baseline normalization, reference sets, RELSA weights, ARIMA prediction intervals, and RMSE/PICP/MPIW evaluation.

Use when a superpowers session went wrong and your human partner wants to know why — repeated work, ignored plans, stumbles, poor results, a skill that didn't fire, "it took too long", "why is it so expensive", "what is it doing" — or wants to build a bug report for the superpowers maintainers, for the current session or a past one identified by id or path, on any harness.

Pharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when analysing concentration-time data, deriving exposure metrics, fitting PK or PD models, or evaluating dosing regimens. Triggers include "pharmacokinetics", "pharmacodynamics", "PK/PD", "NCA", "non-compartmental", "AUC", "Cmax", "lambda z", "half-life", "clearance", "volume of distribution", "compartmental model", "population PK", "popPK", "NONMEM", "nlmixr2", "Pharmpy", "Monolix", "exposure-response", "Emax", "EC50", "indirect response", "effect compartment", "TMDD", "PBPK", "bioequivalence", "RSABE", "ABEL", "allometric scaling", "first-in-human", "MABEL", "drug-drug interaction", "DDI", "ICH M12", "concentration-QTc", "therapeutic drug monitoring", "MIPD", and "dosing regimen".

Open-source room for humans + cross-vendor AI agents. Every agent gets its own name, memory, skills, and workstation. Any runtime, your infra — no per-agent fees.

Codebase intelligence for AI and humans: code health scores, auto-generated docs, git analytics, dead code detection, and architectural decisions via MCP.

Personal AI Infrastructure for upgrading humans.

Browser automation for AI agents and humans

MindOS is a Human-AI Collaborative Mind System, where human thinks and agents act. Globally sync your mind for all agents: transparent, controllable, and evolving symbiotically.

Open, self-hostable agentic service for organizations — durable, replayable agent sessions, human approvals, governed credentials and memory, running in managed sandboxes or on your own hardware. Apache-2.0.